Refreshed after a temporary sabbatical
This is a general view and advisory from me. Long covid has so many manifestations though a patient may be burdened only with two or three or four. It is important for all doctors and physicians and specialists around the world to be fully aware of these manifestations and their background. They must also recognise that much of this could be repeat vaccine mediated. So, if any patient, especially their regular ones, reports a condition not experienced by him before, the doctor must look into the vaccine angle closely and dispassionately, with an open mind. For example, if his 85 year old patient, who has been generally healthy otherwise and conducting himself normally, exhibits early Parkinson’s like symptoms, the vaccination history must be a top consideration. This might require additionally medicines that can clear the resident synthetic virus protein segments in the body, a course of anti histamines possibly. Hope I am making sense, even though I am not a medical practitioner.
Looking forward to new insights into primary pathogenesis, Dr McMillan!
I found this project - The Remission Biome - to be deeply interesting with some important-looking hypotheses and experiences which to my untrained eye link to some of the work of Dr Brogna and colleagues as well as some of your interests. Essentially they are developing protocols for a patient-led initiative arising from their discovery that their long-term ME/CFS went into a short but complete remission when taking antibiotics for unrelated reasons. The project is currently piloting with 50 participants and expanding thereafter.
This comment on Dr Prusty's recent preprint on reactivated viruses gives a very good flavour of the quality of thinking. https://youtu.be/OZfv8xbadxM
"So, the cause is not an immune problem, but rather a persistent infection that results in or produces immune problems."
Dr. Gustavo Aguirre-Chang
It has been shown that
SARS COV-2 INFECTS T LYMPHOCYTES
CAUSING THEIR EXHAUSTION AND APOPTOSIS
CONTRIBUTING TO IMMUNE DYSFUNCTION AND LYMPHOPENIA
THAT FAVORS VIRAL PERSISTENCE
Lymphopenia is associated with a higher Viral Load and Viral Persistence in COVID
SARS COV-2 INFECTS T LYMPHOCYTES CAUSING THEIR EXHAUSTION AND APOPTOSIS CONTRIBUTING TO IMMUNE DYSFUNCTION AND LYMPHOPENIA THAT FAVORS VIRAL PERSISTENCE
⛔️ Jean Michel Wendling "A SARS COV2 reservoir in the intestine is suspected"
⛔️ Guy Van den Eede "see our paper for more evidence."
The Long Covid blood samples were also awash with a category of “exhausted” T cells that can be recognized by certain markers they express. Such cells surge in the ongoing presence of pathogens—suggesting “the bodies of people with Long Covid are actively fighting something,” Putrino says.
Professor Erwin Loh
Stress theory explains COVID, Long COVID, and Sudden Death:
One angle you have not “researched” is the hard data/research of Dr Ana Mihalcea--why is that?
I would consider LC or LV (Long vax) as 75% pathogenic condition and 25% as mitochondrial damage. The second part ha s to be a slow recovery aided by food choice and supplements. There are at least two medical professionals in this sub stack who are following this after they contracted LC. Body can slowly eliminate the first part also on its own whether the pathogenic condition is immune, inflammation or allergy derived or even lingering infection. This can be an even slower process, dragging down the mitochondrial recovery and forcing the LC to last long. This is what they have done taking upto two years for total recovery. I feel the pathogenic part can be safely, securely and quickly handled with a compliment of established medicines, including anti histamines. At least major part of it. This basically entails the flushing out of the residual viral load totally, while working to mitigate the immune, inflammation, allergy or infection. A whole compliment of established medicines clinically thoughtfully chosen. Thus, the body can be freed in time, to focus fully on the mitochondrial recovery and hasten it up. The protocol for this recovery can be rendered less elaborate as a result. In the next meet with experts, especially on LC, I request Dr. McMillan to discuss this template for treating LC. This can apply to patients who could be of LV origin also. The LV/LC picture in the USA appears depressing. The official guidelines seem blinkered. No one is seen to be taking the bull (the issue) by the horn.
The WP reports today that NIH will take up 5 investigations on long covid (atlast 😳), involving patient level trials. It still fails to recognise that the infection may have started it all as long covid, but it could be all about long vax. The first trial will involve residual viral load elimination using courses of Paxlovid. This is classic frog in the well story. Instead of looking at the rich experience from around the world of countries preventing/mitigating/eliminating LC to the point of non existence using classical, time tested medications, NIH believes Paxlovid is the only recourse. So be it. Let us hope something tangible and tenable comes out of these studies, for the sake of millions of unsuspecting Americans long battered by this condition.
VIRAL PERSISTENCE UP TO 2 YEARS POST-COVID
In all participants with Long COVID
SARS-CoV2 was identified in the lamina propria of Rectosigmoid
They had up to 676 days of persistence Post-Acute COVID
Findings support our Protocols with Drugs against Viral Load.
Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19
“We identified that SARS-CoV-2 persistence is one potential driver of this ongoing activated immune state, and we show that SARS-CoV-2 RNA may persist in gut tissue for nearly 2 years after the initial infection.”
I presume that MECFS means “encephalomyelitis and chronic fatigue syndrome." The mRNA “vaccine” introduces the “spike protein” (RNA fragment) into the body, which is tantamount to injecting live virus into systemic circulation, where it attacks the vascular endothelium and propagates throughout the body. Thus damaged, the vascular endothelium allows increased “leakage” of tissue factor into systemic circulation, which activates factor VII. It also releases VWF into circulation, which activates factor VIII. The combined activation of factors VII and VIII increases blood coagulability, which sometimes causes lethal DIC that suddenly obstructs peripheral artery flow. The endothelial damage afflicts all organs and tissues, which explains the wide variety of symptoms associated with the COVID “immunizations, including cardiac myositis, encephalitis, and loss of hair, taste, and smell. It also accelerates capillary senescence, which undermines tissue perfusion and oxygenation, and this accounts for the fatigue, fibromyalgia, and infections. www.stressmechanism.com
Gustavo Aguirre Chang
SARS COV2 INFECTION
TRANSMITTED BY A LUNG TRANSPLANT DONOR
Nasopharyngeal PCR tests were Negative before transplantation
Donor transmission was confirmed by PCR+ of lung Bronchoalveolar lavage (BAL) samples
This is now mandated
so this risk will be reduced
Interview that the Long COVID Apheresis Community carried out on me
Treatment against Viral Load
Therapeutic Test for Viral Persistence
The free Test with which in a few minutes you can perform the Clinical Diagnosis of Microclots/Bioclots
Long Covid Apheresis Community - Expert Interviews: Dr. Gustavo Aguirre-Chang
Gut tissues can retain SARS-CoV-2 particles after COVID-19 infection for more than one year after the resolution of COVID-19
UNDIAGNOSED VIRAL PERSISTENCE
IN 32.5% OF PATIENTS UNDERGOING BARIATRIC SURGERY
All had Negative PCR before Surgery
They were unaware they had a Persistent Infection due to SARS-CoV-2
One part had more than 1 year since infection
Are undiagnosed Long Covid
Lingering SARS-CoV-2 in Gastric and Gallbladder Tissues of Patients with Previous COVID-19 Infection Undergoing Bariatric Surgery